President Trump on Wednesday decried reported health agency efforts to issue stricter guidelines for evaluating a vaccine against COVID-19, accusing the Food and Drug Administration of playing politics.

Trump was apparently reacting to a Tuesday report in the New York Times that said the agency will soon move to tighten requirements for emergency authorization of any coronavirus vaccine to better ensure its safety and effectiveness.

“That has to be approved by the White House. We may or may not approve it. That sounds like a political move,” Trump said during a press briefing at the White House.

“I think that was a political move more than anything else,” he said.

The timing of a vaccine has been an issue of contention between the president and health experts.

Trump has directly contradicted Centers for Disease Control and Prevention Director Robert Redfield on an estimate for widespread release of a vaccine, saying that such distribution of a vaccine would happen before the end of the year. Trump has also said that “every American” will have access to a vaccine by April.

Redfield has testified to Congress that a vaccine would likely not be widely available until next spring or summer.

Multiple potential vaccines are undergoing testing. Top health officials vowed in a hearing on Capitol Hill Wednesday that a COVID-19 vaccine would not be approved until it met “vigorous expectations” for safety and effectiveness.

California will phase out the sale of all gasoline-powered vehicles by 2035 in a bid to lead the U.S. in reducing greenhouse gas emissions by encouraging the state’s drivers to switch to electric cars.

Gov. Gavin Newsom signed an executive order Wednesday that amounts to the most aggressive clean-car policy in the United States. Although it bans the sale of new gas cars and trucks after the 15-year deadline, it will still allow such vehicles to be owned and sold on the used-car market.

“This is the most impactful step our state can take to fight climate change,” the governor said in a statement.

“Our cars shouldn’t make wildfires worse — and create more days filled with smoky air. Cars shouldn’t melt glaciers or raise sea levels threatening our cherished beaches and coastlines.”

Newsom, a Democrat, also threw his support behind a ban on petroleum fracking but called on the California Legislature to make that change.

With extreme wildfires still burning in the state, Newsom says fighting climate change is an emergency. However, the state’s efforts have run afoul of the Trump administration, which has sought to revoke California’s authority to mandate zero-emission vehicles – a challenge that has landed in court.

Transportation is the state’s biggest — and rising — source of emissions, while other sources of emissions, such as from the electricity sector, are falling due to ambitious climate policies.

In January 2018, Gov. Jerry Brown signed an executive order setting ambitious targets of 200 hydrogen fueling stations and 250,000 electric vehicle chargers to support 1.5 million zero-emission vehicles on California roads by 2025.

The number of zero-emission electric vehicles being sold in the state has been on the upswing in recent years, although they accounted for fewer than 8% of all new cars sold in California last year.

The California-based Coalition for Clean Air praised Newsom’s executive order, and the group said it was committed to helping fully implement the new policy.

“The Governor’s Executive Order is a meaningful step in addressing the climate crisis and protecting the health of Californians,” the coalition said in an email to NPR. “Electrifying transportation will also create jobs and help California move forward in its economic recovery.

Jessica Caldwell of Edmunds, the online resource for automobile information, said, “Many automakers have been guilty of setting short-term targets for their electrification strategy that never came to fruition.”

“This rule, if implemented, establishes a specific timeline that they’ll collectively need to adhere to,” Caldwell said. “California is a major market that automakers desperately need to maintain sales.”

A spokesman for the Institute for Energy Research, a think tank that often sides with the fossil fuel industry, called the move by Newsom “another silly distraction from real problems.”

“Driving cars is not what causes forest fires or makes them worse,” David Kreutzer, a senior economist at the institute, told NPR. “If people want to drive electric cars, they’ll buy them. You don’t have to eliminate the competition.”

Kreutzer also pushed back at the notion that electric vehicles are zero-emission. “Electric cars might not have emissions at a tailpipe, but they do have emissions at the power plant,” he said.

In a new court filing, TikTok leaders make clear just how much is at stake in a prolonged battle with the Trump administration: If TikTok were banned for two months, up to half of its users in America would never come back. If the ban persisted for six months, 90% of TikTok users would be gone forever, according to a top TikTok executive.

“We would not be able to make up for lost ground, because people who would have downloaded TikTok will have already turned to other competing platforms such as Byte, Triller, Zynn and the Reels feature on Instagram,” Vanessa Pappas, TikTok’s interim global head, wrote. Pappas’ submission was part of a TikTok lawsuit urging a federal judge to halt a ban on the app from Trump from taking effect on Sunday.

President Trump’s crusade to ban the popular video-sharing app in the U.S. has already cost TikTok millions of dollars in advertising revenue, made it more difficult to recruit new employees and, unless a federal court blocks Trump’s ban from taking effect this weekend, TikTok is facing “catastrophic economic loss,” Pappas said.

Just days ago, Trump indicated that a deal to keep TikTok alive had received his blessing. Under the terms, U.S. software company Oracle would gain control of TikTok’s U.S. user data and, together with Walmart, a one-fifth ownership stake in the app.

But soon TikTok’s Chinese parent company ByteDance, Oracle and Walmart released contradicting statements about key details of the deal, leading to confusion about the actual terms of the agreement and whether or not Trump will approve it.

News of the apparent breakthrough led the Commerce Department to delay for a week its enforcement of Trump’s executive order outlawing business between U.S. citizens and TikTok.

But that order — which would make TikTok disappear from app stores and eventually cripple the app for those who already have it — is set to start now on midnight Sunday.

TikTok’s lawyers are asking for an emergency hearing to prevent the prohibition on TikTok from beginning this weekend. The Justice Department opposes the hearing. In a response to the court, it says while the ban prevents downloads and updates of the app, it will “otherwise largely preserve the status quo” for TikTok users in the U.S.

There is a consensus among Washington lawmakers of both parties that China-based technology companies could pose a national security risk. In its economic trade war with China, the Trump administration has taken aim at a number of Chinese technology firms, but officials in the White House have not provided concrete evidence that TikTok constitutes a specific threat.

Nonetheless, Trump has said that any deal to save TikTok would have to mean that ByteDance, TikTok’s corporate owner, has no power or control, a proposition the company does not appear willing to accept.

Lawyers for TikTok are asking a federal judge to block the order from taking effect, claiming, among other arguments, that Trump’s action violates users’ First Amendment rights.

The president ordered that Chinese-owned app WeChat be effectively shut down in the U.S. along with TikTok, but a federal judge recently blocked that ban over free speech concerns, saying such apps operate as a “a virtual public square.”

In the Wednesday court filing, Pappas, for the first time, spelled out the damage Trump’s clamp down already has caused.

A dozen brands have cancelled or delayed advertising on the app, costing TikTok $10 million in revenue in August alone, she said.

Hiring has become more difficult with a giant target from the White House on its back. Pappas said 52 candidates have declined offers to work at TikTok due to Trump’s attacks against the app.

At the same time, TikTok, which has some 100 million monthly active users in the U.S., has seen explosive growth. Pappas said before rumors started to circulate in July of a looming Trump ban, TikTok had been adding 424,000 new daily users in the U.S. every day.

Regulators in Washington have been conducting a security review of TikTok for more than a year. But in its filing to the court, TikTok lawyers say Trump seemed to step up pressure on the app following a prank in which many TikTok users reserved tickets to the president’s campaign kick-off rally in Tulsa, Okla, then failed to show up.

At any rate, TikTok’s attorneys wrote on Wednesday, Trump “began targeting TikTok, shortly after it surfaced in public reporting that TikTok users had claimed they used the app to coordinate mass ticket reservations for the President’s rally in Tulsa, resulting in an embarrassment for the President’s campaign,” according to lawyer John Hall, who is representing TikTok.

Shortly after, Hall writes, Secretary of State Mike Pompeo confirmed that the administration is “looking at” banning TikTok. Then the president’s re-election campaign ran negative Facebook advertisements urging supporters to sign a petition to ban TikTok.

The Trump campaign has denied the impact of TikTok users on attendance at the Tulsa rally, pointing out that registration was never capped since it was a first-come, first-serve event. Fears over the coronavirus, the Trump campaign says, is what really depressed turnout.

Editor’s note: TikTok helps fund NPR content that appears on the social media platform.