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“It’s the Mike Tyson quote: ‘Everybody’s got a plan until they get punched in the mouth,’” said one person with knowledge of the vaccine effort who’s not authorized to discuss the work. “They are planning. They are competent. It’s just the weight of everything when you sit down in that chair. It’s heavy.”

Biden officials leading the coronavirus response launched a series of regular briefings this week to keep the public informed on the state of the pandemic and government efforts to contain it and rush vaccines out to as many Americans as possible.

But the briefings were short on details. And behind the scenes, officials say, the team was still struggling to get a handle on basic information, liaise with the career government workers who have been running the response and build out a long-term strategy for bringing — and then keeping — the virus under control.

“One of the virtues of a well-run transition is that by the time you take the reins, you have developed some rapport and trust with the career people you’re working with,” the person familiar with the administration’s work said. The “courtship has been unnaturally short,” the person added.

“Nobody had a complete picture,” said Julie Morita, a member of the Biden transition team and executive vice president at the Robert Wood Johnson Foundation. “The plans that were being made were being made with the assumption that more information would be available and be revealed once they got into the White House.”

It’s a steep challenge that Biden officials said they’d been anticipating for weeks, amid a rocky transition period that left them scrambling to piece together vaccine distribution plans and coordinate with state health officials.

Yet in the days since taking over, the Covid response team has confronted a situation that officials described as far worse than expected — and that has prompted public assessments so dour they surprised some who had worked on the administration’s former transition team.

On Tuesday, Biden warned that the “vaccine program is in worse shape than we anticipated or expected,” echoing complaints from his chief of staff, Ron Klain, that a “plan didn’t really exist.”

Biden’s Covid response team has since made a concerted effort not to heap blame on the Trump administration, one official said — even as their vague allusions to a worse-than-expected situation have prompted speculation about what specific problems they’ve encountered.

But people with knowledge of the response detailed fresh concerns that are centered largely on the federal government’s vaccine supply. Biden’s team is still trying to get a firm grasp on the whereabouts of more than 20 million doses of Covid-19 vaccine that the federal government bought and distributed to states but has yet to record as being administered to patients.

Only a small percentage of those unaccounted for doses — roughly 2 million, two officials said — is due to lags in data reporting, the Biden team believes. That would mean the rest of the crucial supply is boxed away in warehouses, sitting idle in freezers or floating elsewhere in the complex distribution pipeline that runs from the administration to individual states.

That’s a dilemma that predated the Biden team’s arrival, with Biden himself hammering the vaccine rollout’s first weeks under the Trump administration as a “dismal failure.”

Yet the response team underestimated at the outset how difficult it would be to fix.

The Biden transition had only received high-level briefings on the distribution effort in the runup to the inauguration on Jan. 20, a transition official said, and was largely kept out of detailed discussions about the on-the-ground operation. The team didn’t get granular access to Tiberius — the central government system used for tracking vaccine distribution — until the transition’s final days.

It was not until after Biden was sworn in that the Covid response team discovered the system was blinded to much of the route that vaccines traveled from the government’s distribution hubs to people’s arms.

Instead, once the vaccine shipments are delivered to the states, responsibility for tracking them has been left up to states’ individual public health systems. The administration then only gets an update once the doses are actually administered and an official record is submitted.

“I think they were really caught off guard by that,” said one adviser. “It’s a mess.”

Top Biden officials have stressed that the missing doses are spread out across the states, which remain largely responsible for getting them to the health providers charged with vaccinating the tens of millions of people waiting in line for shots.

But the Covid team has since had to spend hours on the phone with various state officials trying to manually track down the unused doses, a time-consuming task that’s sapped resources and has yet to give officials a full picture of where exactly supplies are going.

They’ve also sought to persuade health providers to stop holding doses in reserve, a practice borne out of concerns people wouldn’t be able to get the second shot of their two-dose regimen — but one that’s no longer necessary and has only contributed to the confusion, according to two people with knowledge of the discussions.

On a call with White House officials Tuesday, Arkansas Republican Gov. Asa Hutchinson vented that some states are bearing the brunt of the blame for the uneven rollout because of those reserves — a nuance not reflected in the federal numbers, according to notes of the call obtained by POLITICO.

The complaint prompted a pledge from Centers for Disease Control and Prevention Director Rochelle Walensky to issue clearer guidance for how states should manage their allocated vaccines.

Illinois Democratic Gov. J.B. Pritzker later blamed a Trump administration program that designated pharmacies to distribute vaccines to long-term care facilities for “bringing our numbers way down” because of how slow it has been to get shots in arms.

The White House has since given states permission to seize unused doses from the pharmacy program and reallocate them elsewhere.

“There is no doubt they are doing a better job,” George Helmy, the chief of staff for New Jersey Democratic Gov. Phil Murphy, said about the Biden administration. “We have a true partner who is being transparent and collaborative.”

As they grapple with the immediate distribution issues, federal officials have also raced to build out detailed plans for eventually distributing the shots to broader populations beyond health care workers and older Americans — a project that people familiar with the effort say the Trump administration never even started on.

And though the Biden team had planned to boost the pace of vaccine manufacturing over time, some Biden officials said they were shocked to learn soon after Inauguration Day that there was little in the federal vaccine reserve — and that the companies producing the shots were nowhere near capable of churning out as many doses as the Trump administration had projected in the preceding months.

The Biden administration has since warned that supplies will remain limited until the summer, raising the possibility of ongoing shortages even as the nation’s daily vaccination rate picks up.

The White House cheered promising data on a new single-dose vaccine from Johnson & Johnson on Friday. But production obstacles have dampened expectations for its immediate impact, with one federal official likening the anticipated early flow of shots to “a trickle.”

That has turned the Covid team’s first days into something closer to a triage operation than the more orderly rollout that the administration had hoped for, especially as much of the federal health department operates on a skeleton staff made up of career officials and a handful of early political appointees.

And though the Biden administration is still pressing ahead with building mass vaccination sites and long-planned preparations for the long-term response effort, officials said the time lost navigating this early set of difficulties has set back a response already likely to consume much of Biden’s first year in office.

“This isn’t over any time soon,” said Craig Fugate, a former Obama administration FEMA administrator who worked on the transition. “There may not be a bright red line where when we cross that line we’re done, we’re finished and everything’s going to be great.”

Rachel Roubein contributed to this report.