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LONDON — Europe is slipping behind in its vaccination drive and could see hundreds of thousands more deaths by next spring, the World Health Organization has said.

“We’ve only got 54% of the one billion people living in Europe fully vaccinated,” Robb Butler, executive director for WHO Europe, told CNBC Wednesday.

This region for the U.N. health agency comprises of 53 countries that actually spans Europe and Central Asia and has approximately 900,000 citizens at its last count.

“There are [around] 45% who are unvaccinated or not fully vaccinated, that’s a bigger issue for our policy and decision-makers right now — driving up vaccination rates,” he told CNBC’s “Squawk Box Europe” on Wednesday.

Butler’s comments come as Europe struggles with the latest wave of Covid infections, prompting further restrictive measures and pushing hospitalizations higher.

Most, if not all, of the people who have been admitted to hospital intensive care wards with Covid are unvaccinated, health officials from across the region have reported. Covid vaccines cannot stop transmission of the virus entirely but they greatly reduce the risk of severe infection, hospitalization and death.

WHO Europe’s large proportion of unvaccinated people puts it at risk of excess deaths in the months to come, the WHO warned on Tuesday, issuing a statement in which is said that the Covid death toll in Europe and Central Asia could rise by 700,000 to reach more than 2.2 million by next March.

The Europe region has already recorded 1.5 million Covid deaths, with the virus now becoming the leading cause of death in both Europe and Central Asia, WHO’s Europe branch said.

The region is currently experiencing nearly 4,200 deaths per day, twice the daily deaths recorded at the end of September, the statement noted.

WHO has repeatedly stated that Europe is at the epicenter of the latest global wave of Covid infections. Vaccination rates, both of the initial Covid vaccination programs and booster shots, differ widely from country to country.