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Mr. Trump also hosted a large gathering in the Rose Garden for his Supreme Court nominee, Judge Amy Coney Barrett, where at least eight people, including the president, may have become infected. The White House has chosen not to trace the contacts of guests and staff members from that event.

Mrs. Trump has generally taken a more cautious approach than her husband to the virus and has not minimized its effects the way her husband has.

Mr. Trump has downplayed his symptoms, including a shortness of breath, and focused only on trying to demonstrate that he has recovered. Mrs. Trump, on the other hand, described the “roller coaster” symptoms she experienced in a statement on Wednesday titled “My Personal Experience With Covid-19,” her first extensive update on her health since the announcement that she had tested positive.

“I experienced body aches, a cough and headaches, and felt extremely tired most of the time,” she said.

Mrs. Trump, who had not been seen or heard from since the positive test announcement, said that she had spent her recovery “reflecting on my family,” and that she hoped “to resume my duties as soon as I can.”

She added, “I also thought about the hundreds of thousands of people across our country who have been impacted by this illness that infects people with no discrimination.”

Just as she did during her speech at the Republican National Convention, Mrs. Trump acknowledged the effects of the virus on Americans across the country. Mr. Trump, in contrast, emerged from his own hospitalization for the coronavirus with a less empathetic message: “Don’t let it dominate your life.”