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The man’s friend and his family remained isolated at home in New Rochelle, Mr. Cuomo said. The three children, two sons and a daughter, who tested positive for the virus attended the Westchester Torah Academy in White Plains, N.Y. The man’s fourth child, a daughter, did not test positive for the virus.

The authorities announced the state’s first confirmed case of the new coronavirus on Sunday, saying a 39-year-old health care worker had been infected in Iran, where the illness is raging. She began exhibiting symptoms after returning home but had kept herself largely isolated.

Her husband had also been tested for the virus. The tests came back negative, but the man was being asked to remain in isolation, Mr. de Blasio said on Wednesday.

With the virus spreading, around 300 students and faculty at State University of New York and City University of New York campuses who were studying abroad in China, Italy, Japan, Iran and South Korea — all of which have been epicenters of the illness — would be asked to come back to the United States, Mr. Cuomo said.

They would travel back to the U.S. on a chartered plane and be quarantined upon arrival for two weeks, Mr. Cuomo said. The state was identifying dormitories where they would be isolated.

Several New York City employees not connected to the Westchester case, including five police officers and one public-school teacher, all of whom had traveled to an affected country, were self-isolating as a precaution, Mr. de Blasio said. Officials had not yet tested them for the virus but planned to, he said.

Mr. de Blasio said that the teacher was “not in contact with students and won’t be in contact with students until it is safe to be so.”