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Ms. Harris is certain to draw speculation as a potential running mate for Mr. Biden.

Ms. Harris made her endorsement after the primary race narrowed to what is effectively a two-person race between Mr. Biden and Senator Bernie Sanders of Vermont. Moderate-leaning Democrats have rapidly coalesced behind Mr. Biden, whose campaign has been rolling out new endorsements seemingly nonstop in recent days.

In a written statement about her endorsement, Ms. Harris noted the absence of a top female candidate in the primary. “Like many women, I watched with sadness as women exited the race one by one,” she said, adding that “we find ourselves without any woman on a path to be the Democratic nominee for president.”

“This is something we must reckon with and it is something I will have more to say about in the future,” Ms. Harris said. “But we must rise to unite the party and country behind a candidate who reflects the decency and dignity of the American people and who can ultimately defeat Donald Trump.”

Ms. Harris ended her presidential bid in December, two months before the Iowa caucuses. Now, she is following several of her former rivals for the presidential nomination in getting behind Mr. Biden. Senator Amy Klobuchar of Minnesota, former Mayor Pete Buttigieg of South Bend, Ind., and former Mayor Michael R. Bloomberg of New York left the race last week and endorsed the former vice president. Former Representative Beto O’Rourke of Texas also backed Mr. Biden last week.

Ms. Harris’s endorsement was announced five days after Super Tuesday, when Mr. Biden captured 10 of 14 states, and ahead of another round of contests two days from now in six states, including Michigan.