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Centrist Democrats, of course, think just the opposite. Mr. Biden, the former vice president, even after facing intense media scrutiny and racking up a number of self-inflicted errors, still fares slightly better in head-to-head polling against Mr. Trump than either of the two progressive front-runners.

Yet it was the combined strength of Ms. Warren and Mr. Sanders, along with Mr. Biden’s fund-raising and debate difficulties, that frightened moderates enough to lure former Mayor Michael R. Bloomberg of New York and former Gov. Deval Patrick of Massachusetts into the race. Now, though, it’s the left wing of the party that’s growing anxious about how to avoid its own debacle.

A handful of leaders from progressive labor unions have had initial conversations about if, when and how to collectively endorse a candidate and are planning to meet after the holidays, according to a Democrat familiar with the discussions.

Larry Cohen, the former president of the Communications Workers of America, is already thinking well ahead of that. Mr. Cohen supports Mr. Sanders but that prefers Ms. Warren stay in the race throughout the primary election to deny a moderate from accumulating a delegate majority. If Mr. Sanders doesn’t win outright, he said, the two progressives should demonstrate their combined strength, and amass over half the pledged delegates, so that the left has an upper hand going into next summer’s Democratic convention.

Mr. Cohen has been more aggressively making his case to other progressives about how both candidates should stockpile delegates, including over dinner last week with other Sanders supporters.

But in the near term, he and other left-wing organizers are mostly trying to keep the primary-within-a-primary between Mr. Sanders and Ms. Warren from growing contentious.

On a conference call last month organized by Our Revolution, the Sanders-aligned progressive group, Ms. Jayapal and Mr. Cohen both urged activists to exert pressure on House Democrats to support “Medicare for all” while highlighting the common ground of the two presidential hopefuls.