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One witness described seeing the police shoot a man who was wielding a knife.

As the police cordoned off the area, empty buses and abandoned vehicles remained parked on the bridge. In the nearby Borough Market, a food and drink space that is popular with tourists, visitors were told to shelter in place, before eventually being evacuated.

Mayor Sadiq Khan of London said in a statement that he was in close contact with the police, and urged those in the city to follow police directions.

“We must — and we will — stay resolute in our determination to stand strong and united in the face of terror,” he said. “Those who seek to attack us and divide us will never succeed.”

The British Transport Police said that the nearby London Bridge station, one of the city’s busiest transit hubs, had been closed.

John McManus, a BBC reporter who was crossing the bridge at the time of the incident, told the news outlet that he had seen a group of men involved in a fight with another man on the bridge. The police then arrived, and “a number of shots were fired at this man.”

Matthew Marchand, 37, whose office faces the bridge, said it was “scary to think that this happens on your doorstep somehow.”