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Part of the challenge is that the unvaccinated live in communities dotted throughout the United States, in both lightly and densely populated counties. Though some states like Missouri and Arkansas have significantly lagged the nation in vaccination rates, unvaccinated Americans are, to varying degrees, everywhere: In Cook County, Ill., which includes Chicago, 51 percent of residents are fully vaccinated. Los Angeles County is barely higher, at 53 percent. In Wake County, N.C., part of the liberal, high-tech Research Triangle area, the vaccination rate is 55 percent.

The rate of vaccinations across the country has slowed significantly since April, but there are signs in recent days of a new rise in shots being distributed, with upticks in vaccinations particularly in states like Arkansas, Louisiana and Missouri, where cases have grown. As of Friday, about 652,000 doses, on average, were being given each day, according to data from the Centers for Disease Control and Prevention; that was up from recent weeks, when the country hovered just above 500,000 shots a day. Nationwide, about 97 percent of people hospitalized with Covid-19 are unvaccinated, federal data shows.